PAPPA2 antibody (N-Term)

Catalog No. ABIN2775475

This anti-PAPPA2 antibody is a Rabbit Polyclonal antibody detecting PAPPA2 in WB. Suitable for Human, Rat and Guinea Pig.

Quick Overview for PAPPA2 antibody (N-Term) (ABIN2775475)

Target: PAPPA2 (Pappalysin 2 (PAPPA2))

Reactivity: Human, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPPA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAPPA2 Antibody

Binding Specificity: N-Term

Sequence: PPDLTENPAG LRGAVEEPAA PWVGDSPIGQ SELLGDDDAY LGNQRSKESL

Predicted Reactivity: Guinea Pig: 85%, Human: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against PAPPA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAPPA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 827 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAPPA2

Target: PAPPA2 (Pappalysin 2 (PAPPA2))

Alternative Name: PAPPA2

Background: PAPPA2 is a metalloproteinase which specifically cleaves IGFBP-5. It shows limited proteolysis toward IGFBP-3.
Alias Symbols: PAPP-A2, PAPPE, PLAC3
Protein Interaction Partner: ZNF512B, SMAD4, ATF7IP, IGFBP5, IGFBP3,
Protein Size: 827

Molecular Weight: 92 kDa

Gene ID: 60676

NCBI Accession: NM_021936, NP_068755

UniProt: A9Z1Y8